SCHEMBL11060919

SCHEMBL11060919

Cc1c(O)c(C)c(Cl)c(O)c1O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP3A4 P08684 1/20 0.33
CHRM1 P11229 1/20 0.33
ALOX15 P16050 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CASP1 P29466 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3221262 0.90 HPGD (0.39) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL3308498 0.88 TSHR (0.44) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL5587483 0.83 HPGD (0.44) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL17490271 0.83 HPGD (0.44) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL5586757 0.81 HPGD (0.37) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL5590229 0.81 TSHR (0.53) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL9650992 0.80 HPGD (0.41) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL24462646 0.78 HPGD (0.39) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL10922334 0.78 HPGD (0.47) HPGDTSHRHSD17B10ALDH1A1MAPT
SCHEMBL16379922 0.78 HPGD (0.39) HPGDTSHRHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed