Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651210 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KMT2AL3MBTL1TDP1MAPK1 | |
| SCHEMBL9651333 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL9651332 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL9651031 | 0.83 | HTT (0.45) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL27278510 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1TDP1MAPK1 | |
| SCHEMBL9651180 | 0.80 | ELANE (0.38) | ALDH1A1L3MBTL1TDP1MAPK1CA4 | |
| SCHEMBL9651176 | 0.80 | ELANE (0.38) | ALDH1A1L3MBTL1TDP1MAPK1CA4 | |
| SCHEMBL9650263 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPT | |
| SCHEMBL9651082 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1TDP1MAPK1 | |
| SCHEMBL9651088 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246603-B1 | 4-HALOGENO-2-OXYIMINO-3-OXOBUTYRIC ACIDS | Takeda Chemical Industries, Ltd. (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-4845257-A | 4-halogeno-2-oxyimino-3-oxobutyric acids and derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-04 | — | — | US | disclosed |