Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914769 | 0.92 | AURKA (0.36) | DAOHDAC8HDAC6AURKAAURKB | |
| Methyl Alcohol SCHEMBL10895232 | 0.92 | DAO (0.36) | DAOHDAC8HDAC6AURKAAURKB | |
| SCHEMBL79800 | 0.82 | LTA4H (0.50) | KDM4EMAPT | |
| SCHEMBL14353589 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL29171477 | 0.80 | LTA4H (0.48) | KDM4EMAPT | |
| SCHEMBL28464217 | 0.77 | TSHR (0.33) | DAOAURKAAURKBINCENPNAPRT | |
| SCHEMBL354072 | 0.77 | — | — | |
| SCHEMBL1680364 | 0.77 | — | — | |
| SCHEMBL182793 | 0.77 | — | — | |
| SCHEMBL11386377 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) | 2025-09-25 | — | — | US | claimed |
| WO-2025021115-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2025-01-30 | — | — | WO | claimed |
| CN-117617045-A | Green prevention and control planting method for peach tree diseases and insect pests | 上海市农业技术推广服务中心 | 2024-03-01 | — | — | CN | claimed |
| CN-116616304-A | Azolyl ether and tebuconazole suspending agent and preparation method thereof | 江苏东南植保有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-114532334-B | Azole ether and fine nail cream granules and preparation method thereof | 山东汤普乐作物科学有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-115500220-A | Planting method of muskmelons | 青白(天津)农业科技有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-113549053-B | Pyrazoloquine (azolyl) ether compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-114532334-A | Azole ether and fine nail cream granules and preparation method thereof | 山东汤普乐作物科学有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-0342150-A1 | Substituted azole ethers, their preparation and use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-15 | — | — | EP | claimed |
| EP-0307791-A1 | Bisazolyl-hydroxyalkyl derivatives | BAYER AG (DE) | 1989-03-22 | — | — | EP | claimed |
| US-12612383-B2 | Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof | SHANGHAI WENNAI THERAPEUTICS CO., LTD. (CN) | 2026-04-28 | — | — | US | disclosed |
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) | 2025-09-25 | — | — | US | disclosed |
| CN-119790050-A | Oxazole TRPML1 agonists and uses thereof | 利布拉医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119546588-A | Pyridine checkpoint kinase 1 (CHK 1) inhibitors and uses thereof | 无界生物公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2025021115-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |
| EP-0342150-A1 | Substituted azole ethers, their preparation and use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-15 | — | — | EP | disclosed |
| EP-0342150-A1 | Substituted azole ethers, their preparation and use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-15 | — | — | EP | disclosed |
| EP-0308782-A2 | Antimycotic preparations | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |
| EP-0307791-A1 | Bisazolyl-hydroxyalkyl derivatives | BAYER AG (DE) | 1989-03-22 | — | — | EP | disclosed |
| EP-0199168-A1 | Bisazolyl ether carbinols | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296922-A1 | POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | SCN8A, SCN11A, TRPV1 | DAO 3110/4885HDAC8 137/4885HDAC6 342/4885 |
| US-12612383-B2 | Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof | SCN8A, SCN11A, TRPV1 | DAO 2936/4885HDAC8 187/4885HDAC6 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.