Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929633 | 0.90 | CSF1R (0.75) | CSF1R | |
| SCHEMBL9650918 | 0.88 | CSF1R (0.58) | CSF1RTP53MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7187992 | 0.87 | ATP4A (0.64) | — | |
| SCHEMBL11229376 | 0.87 | MAPT (0.69) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9652863 | 0.85 | CSF1R (0.54) | CSF1RTP53MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9653897 | 0.84 | ATP4A (0.58) | CSF1R | |
| SCHEMBL5929654 | 0.81 | CSF1R (0.75) | CSF1R | |
| SCHEMBL5929784 | 0.81 | CSF1R (0.62) | CSF1RKDM4E | |
| SCHEMBL5930153 | 0.79 | CSF1R (0.66) | CSF1R | |
| SCHEMBL5929776 | 0.78 | CSF1R (0.61) | CSF1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259174-B1 | DERIVATIVES OF 4-AMINOQUINOLINE AND THEIR USE AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-18 | — | — | EP | claimed |