Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.69 |
| ▸ | DRD3 | P35462 | 6/20 | 0.69 |
| ▸ | DRD4 | P21917 | 4/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653912 | 0.97 | DRD2 (0.74) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL9652784 | 0.94 | DRD2 (0.72) | DRD2DRD4HTR1AADRA2AADRA1A | |
| SCHEMBL14761584 | 0.85 | DRD2 (0.94) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL3162960 | 0.83 | DRD2 (0.76) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL6357580 | 0.83 | DRD3 (0.94) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL10910646 | 0.82 | DRD2 (0.94) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL8980577 | 0.82 | DRD2 (0.75) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL14761722 | 0.82 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9134513 | 0.82 | DRD3 (0.91) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL9653853 | 0.81 | DRD2 (0.71) | DRD2DRD3DRD4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496692-A1 | 2-Methoxyphenylpiperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-07-29 | — | — | EP | claimed |