Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695271 | 0.88 | HRH3 (0.60) | HRH3 | |
| SCHEMBL8907631 | 0.85 | HRH3 (0.60) | HRH3SYKLOXL2HTR1AADRA1D | |
| SCHEMBL8912787 | 0.85 | HRH3 (0.60) | HRH3SYKLMNASMN1; SMN2LOXL2 | |
| SCHEMBL1695377 | 0.83 | HRH3 (0.54) | HRH3SYKLMNAADRA1D | |
| SCHEMBL16596266 | 0.81 | HRH3 (0.64) | HRH3SYKLOXL2HTR1AADRA1D | |
| SCHEMBL11751268 | 0.80 | HRH3 (0.57) | HRH3SYKLMNALOXL2HTR1A | |
| SCHEMBL15453257 | 0.78 | HRH3 (0.56) | HRH3SYKSMN1; SMN2LOXL2HTR1A | |
| SCHEMBL15453232 | 0.78 | HRH3 (0.56) | HRH3LOXL2HTR1AADRA1DADRA1A | |
| SCHEMBL30240776 | 0.75 | DNM1 (0.41) | — | |
| SCHEMBL5241892 | 0.75 | HRH3 (0.47) | HRH3LOXL2HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102892-A | Antisecretory agent for gastrointestinal disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |