Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810984 | 0.81 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL28646147 | 0.75 | S100A4 (0.36) | PTPN1 | |
| SCHEMBL7432077 | 0.70 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL30716074 | 0.70 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL6648541 | 0.70 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL6649254 | 0.66 | P2RY6 (0.36) | — | |
| SCHEMBL28455735 | 0.65 | MAOB (0.39) | KDM4EPTPN1MAOB | |
| SCHEMBL8078213 | 0.65 | PTPN1 (0.40) | AKR1A1AKR1B1MAPK14KDM4EPTPN1 | |
| SCHEMBL9642237 | 0.62 | MAPT (0.59) | AKR1A1AKR1B1KDM4EPTPN1 | |
| SCHEMBL10560302 | 0.61 | PTPN1 (0.43) | KDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151544-A | Intermediates in the preparation of chiral spirofluorenehydantoins | ALCON LABORATORIES, INC. (US) | 1992-09-29 | — | — | US | disclosed |
| US-5151544-A | Intermediates in the preparation of chiral spirofluorenehydantoins | ALCON LABORATORIES, INC. (US) | 1992-09-29 | — | — | US | disclosed |