Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888139 | 0.85 | EPHX1 (0.54) | EPHX1GAASMN1; SMN2RAB9ACNR1 | |
| SCHEMBL643094 | 0.84 | EPHX1 (0.48) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL965953 | 0.82 | EPHX1 (0.43) | EPHX1GAASMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL8851435 | 0.82 | EPHX1 (0.50) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL9652386 | 0.81 | EPHX1 (0.48) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL20660536 | 0.80 | EPHX1 (0.52) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL953293 | 0.79 | GNAI3 (0.55) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL25500360 | 0.79 | EPHX1 (0.50) | EPHX1GAASMN1; SMN2RAB9ACNR1 | |
| SCHEMBL883979 | 0.78 | EPHX1 (0.53) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL19086743 | 0.78 | EPHX1 (0.46) | EPHX1POLBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |