Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653347 | 1.00 | LMNA (0.42) | LMNAGAASMN1; SMN2POLQTAS2R14 | |
| SCHEMBL9652142 | 0.82 | LMNA (0.43) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL9652138 | 0.82 | LMNA (0.43) | LMNAGAATAS2R14KCNK3KCNK9 | |
| SCHEMBL9653782 | 0.81 | SMN1; SMN2 (0.38) | LMNAGAASMN1; SMN2POLQCTNNB1 | |
| SCHEMBL9653791 | 0.81 | SMN1; SMN2 (0.38) | LMNAGAASMN1; SMN2POLQCTNNB1 | |
| SCHEMBL9653695 | 0.78 | KMT2A (0.43) | LMNAGAASMN1; SMN2HPGD | |
| SCHEMBL9652085 | 0.78 | POLB (0.46) | HPGDDHODH | |
| SCHEMBL9652697 | 0.78 | HPGD (0.39) | LMNAGAASMN1; SMN2HPGDDHODH | |
| SCHEMBL9652081 | 0.78 | POLB (0.46) | HPGDDHODH | |
| SCHEMBL9652704 | 0.78 | HPGD (0.39) | LMNAGAASMN1; SMN2HPGDDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |