Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 3/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | CBS | P35520 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75506 | 0.98 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL865705 | 0.95 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| Methacrylic Acid SCHEMBL28074348 | 0.93 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| Propionic Acid SCHEMBL29930795 | 0.91 | THRB (0.48) | TSHRTHRBALDH1A1TDP1POLB | |
| Methacrylic Acid SCHEMBL8424556 | 0.91 | TSHR (0.47) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL14489333 | 0.89 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| Phosphoric Acid SCHEMBL3949060 | 0.89 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL2222187 | 0.89 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| Phosphoric Acid SCHEMBL3957005 | 0.89 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL14489044 | 0.89 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104929-A | With a protic group-substituted ester or amide of acrylic or methacrylic acid; curable; transparent; durable | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0337695-A2 | Abrasion resistant coatings comprising silicon dioxide dispersions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-18 | — | — | EP | disclosed |