Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 12/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 12/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 12/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 12/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9011811 | 0.98 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL9011826 | 0.72 | NPSR1 (0.36) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9011806 | 0.72 | NPSR1 (0.36) | L3MBTL1 | |
| SCHEMBL9011583 | 0.69 | KMT2A (0.36) | — | |
| SCHEMBL9011584 | 0.69 | KMT2A (0.36) | — | |
| SCHEMBL10415149 | 0.66 | HTR2A (0.36) | TAAR1F2 | |
| SCHEMBL1225030 | 0.66 | CYP2D6 (0.39) | TAAR1F2 | |
| SCHEMBL3249480 | 0.65 | HTR2A (0.34) | TAAR1F2L3MBTL1 | |
| SCHEMBL27746192 | 0.65 | CES1 (0.36) | TAAR1ESR1L3MBTL1 | |
| SCHEMBL914608 | 0.62 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488897-A1 | New guanidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-06-03 | — | — | EP | disclosed |