Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011584 | 1.00 | KMT2A (0.36) | KMT2AMIFRIPK1MAPTALDH1A1 | |
| SCHEMBL12756966 | 0.73 | KMT2A (0.41) | KMT2AMIFRIPK1MAPTALDH1A1 | |
| SCHEMBL7500324 | 0.72 | DPP4 (0.39) | KMT2AMIFALDH1A1LMNA | |
| SCHEMBL9654062 | 0.69 | GRIN2D (0.44) | — | |
| SCHEMBL1225030 | 0.69 | CYP2D6 (0.39) | KMT2ALMNAMAPK1 | |
| SCHEMBL10415149 | 0.69 | HTR2A (0.36) | MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9011811 | 0.68 | GRIN2D (0.46) | — | |
| SCHEMBL9016418 | 0.68 | CYP1A2 (0.47) | KMT2AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL3249480 | 0.67 | HTR2A (0.34) | ALDH1A1LMNA | |
| SCHEMBL7715366 | 0.65 | NPSR1 (0.43) | KMT2AALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494934-A | ANTIDEPRESSANTS, HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1996-02-27 | — | — | US | disclosed |
| US-5296498-A | Guanidine compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| EP-0488897-A1 | New guanidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-06-03 | — | — | EP | disclosed |