SCHEMBL9654087

SCHEMBL9654087

CCCCCCC[Si](C)(C)c1ccc(OCC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.48
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
RAB9A P51151 3/20 0.43
MAPT P10636 2/20 0.43
NR5A1 Q13285 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CNR1 P21554 3/20 0.39
CNR2 P34972 3/20 0.39
TP53 P04637 3/20 0.39
LTA4H P09960 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
NPC1 O15118 2/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618130 1.00 NQO1 (0.48) NQO1NR1H2NR1H3RAB9AMAPT
SCHEMBL18717595 0.81 NR1H2 (0.59) NR1H2NR1H3CNR1CNR2
SCHEMBL12606086 0.79 NR1H2 (0.46) NR1H2NR1H3TSHRCNR1CNR2
SCHEMBL16671999 0.78 NR1H2 (0.49) NR1H2NR1H3L3MBTL1SMN1; SMN2CNR1
SCHEMBL17124988 0.77 NR1H2 (0.63) NR1H2NR1H3CNR1CNR2
SCHEMBL23794973 0.77 NR1H2 (0.47) NR1H2NR1H3TSHRCNR1CNR2
SCHEMBL1782896 0.77 NR1H2 (0.47) NR1H2NR1H3CNR1CNR2
SCHEMBL12619325 0.77 NR1H2 (0.47) NR1H2NR1H3RAB9AMAPTALDH1A1
SCHEMBL7455113 0.77 NR1H2 (0.47) NR1H2NR1H3RAB9AMAPTL3MBTL1
SCHEMBL3433471 0.77 NR1H2 (0.47) NR1H2NR1H3RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117028-A Catalysis with hexachloroplatinic acid; hydrosilation HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed