Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654364 | 1.00 | PLG (0.46) | PLGPLATLMNAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10621242 | 0.98 | PLG (0.44) | PLGPLATLMNAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10621245 | 0.98 | PLG (0.44) | PLGPLATLMNAMAPTKDM4E | |
| SCHEMBL5789042 | 0.81 | PLG (0.53) | PLGPLATLMNAMAPTF2 | |
| SCHEMBL688602 | 0.81 | PLG (0.53) | PLGPLATLMNAMAPTF2 | |
| Hydrochloric Acid SCHEMBL11075182 | 0.80 | PLG (0.52) | PLGPLATLMNAMAPTF2 | |
| Hydrochloric Acid SCHEMBL1068668 | 0.80 | PLG (0.52) | PLGPLATLMNAMAPTF2 | |
| SCHEMBL13601550 | 0.77 | KDM4E (0.44) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23254519 | 0.76 | PLG (0.52) | PLGPLATLMNAMAPTF2 | |
| Hydrochloric Acid SCHEMBL10977829 | 0.75 | PLG (0.55) | PLGPLATLMNAMAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278977-B1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | Bundgaard, Hans (DK) | 1992-05-06 | — | — | EP | disclosed |