Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127020 | 0.94 | GAA (0.43) | GAAPOLBALOX5KMT2AMEN1 | |
| SCHEMBL20096147 | 0.94 | KMT2A (0.43) | GAAPOLBKMT2AMEN1PIK3CD | |
| SCHEMBL27819988 | 0.92 | KMT2A (0.43) | GAAPOLBKMT2AMEN1PIK3CD | |
| SCHEMBL9654293 | 0.88 | GAA (0.44) | GAAALOX5KMT2AMEN1PIK3CD | |
| SCHEMBL9549183 | 0.87 | GAA (0.39) | GAAPOLBALOX5KMT2AMEN1 | |
| SCHEMBL9126070 | 0.87 | SMN1; SMN2 (0.45) | KMT2AMEN1PIK3CDADRA1BSMN1; SMN2 | |
| SCHEMBL8559681 | 0.87 | ADRA1B (0.46) | POLBKMT2AMEN1PIK3CDADRA1B | |
| SCHEMBL13895035 | 0.87 | PIK3CD (0.46) | POLBKMT2AMEN1PIK3CDADRA1B | |
| SCHEMBL9122160 | 0.86 | GAA (0.43) | GAAALOX5PIK3CDLTA4H | |
| SCHEMBL9122920 | 0.86 | GAA (0.43) | GAAALOX5PIK3CDLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241050-B1 | AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATION CONTAINING THE ABSORPTION PROMOTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4882359-A | USED WITH DRUGS | HISAMITSU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| WO-1987006226-A2 | AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATIONS CONTAINING THE ABSORPTION PROMOTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-22 | — | — | WO | disclosed |
| EP-0241050-A2 | Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparation containing the absorption promoters | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-14 | — | — | EP | disclosed |