⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL18394942 | 0.91 | SLC34A1 (0.32) | — | |
| Lithium Ion SCHEMBL21749343 | 0.91 | — | — | |
| SCHEMBL920065 | 0.79 | — | — | |
| SCHEMBL486485 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL7860312 | 0.73 | — | — | |
| Lithium Ion SCHEMBL21749348 | 0.73 | — | — | |
| Silver SCHEMBL555009 | 0.73 | — | — | |
| SCHEMBL4823616 | 0.73 | — | — | |
| SCHEMBL553542 | 0.73 | — | — | |
| Potassium Ion SCHEMBL553768 | 0.73 | SLC34A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134146-A | SUBSTITUTED OXADIAZOLES AND THIADIAZOLES FOR USE IN THE TREATMENT OF GLAUCOMA | MERCK SHARP AND DOHME LTD. (GB) | 1992-07-28 | — | — | US | disclosed |
| US-5106853-A | Selective muscarinic agonist | MERCK SHARP & DOHME, LTD. (GB) | 1992-04-21 | — | — | US | disclosed |
| EP-0459568-A2 | Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use | MERCK SHARP & DOHME LTD. (GB) | 1991-12-04 | — | — | EP | disclosed |
| EP-0398629-A2 | An oxadiazole and its salts, their use in treating dementia, their preparation and formulations | MERCK SHARP & DOHME LTD. (GB) | 1990-11-22 | — | — | EP | disclosed |