Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555779 | 0.81 | FGFR1 (0.38) | HTTCYP3A4SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9555783 | 0.81 | FGFR1 (0.38) | HTTCYP3A4SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4273007 | 0.81 | CYP3A4 (0.38) | HTTCYP3A4SMN1; SMN2GAASMYD2 | |
| SCHEMBL2913457 | 0.80 | CYP3A4 (0.37) | HTTCYP3A4SMN1; SMN2SMYD2 | |
| SCHEMBL1504056 | 0.78 | CYP2C9 (0.40) | HTTCYP3A4SMN1; SMN2CYP2C9POLB | |
| SCHEMBL2914122 | 0.78 | CYP3A4 (0.40) | HTTCYP3A4SMN1; SMN2SMYD2 | |
| SCHEMBL6053703 | 0.78 | CYP3A4 (0.40) | HTTCYP3A4SMN1; SMN2SMYD2 | |
| SCHEMBL6053844 | 0.78 | CYP3A4 (0.40) | HTTCYP3A4SMN1; SMN2SMYD2 | |
| SCHEMBL28944727 | 0.77 | SRC (0.39) | HTTCYP3A4SMN1; SMN2GAACYP2C9 | |
| SCHEMBL30563707 | 0.77 | SMYD2 (0.36) | HTTCYP3A4SMN1; SMN2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479640-A2 | Novel phosphonate derivatives of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-08 | — | — | EP | disclosed |