Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555783 | 1.00 | FGFR1 (0.38) | FGFR1SLC22A6TYMPCYP3A4HTT | |
| SCHEMBL9555572 | 0.85 | PPARA (0.36) | CYP3A4HTTSMN1; SMN2TSHR | |
| SCHEMBL9555574 | 0.85 | PPARA (0.36) | CYP3A4HTTSMN1; SMN2TSHR | |
| SCHEMBL9655148 | 0.81 | HTT (0.40) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL34465055 | 0.81 | PRKCA (0.34) | CYP3A4HTTSMN1; SMN2TSHRMEN1 | |
| SCHEMBL20254087 | 0.80 | CYP2C9 (0.41) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL9009116 | 0.80 | CYP2C9 (0.41) | CYP3A4HTTSMN1; SMN2SMYD2TSHR | |
| SCHEMBL28665561 | 0.77 | SMN1; SMN2 (0.37) | CYP3A4HTTSMN1; SMN2SMYD2PKM | |
| SCHEMBL28665559 | 0.77 | SMN1; SMN2 (0.37) | CYP3A4HTTSMN1; SMN2SMYD2PKM | |
| SCHEMBL21873649 | 0.75 | CYP1A2 (0.42) | CYP3A4HTTSMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |