Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657052 | 0.85 | SMN1; SMN2 (0.50) | CREBBPALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL9658194 | 0.84 | CREBBP (0.43) | CREBBPALDH1A1MAPTHPGDPRKCI | |
| SCHEMBL9656898 | 0.84 | CREBBP (0.43) | CREBBPALDH1A1MAPTHPGDPRKCI | |
| SCHEMBL9657506 | 0.84 | PARP10 (0.50) | CREBBPALDH1A1MAPTHPGDPRKCI | |
| SCHEMBL11603912 | 0.82 | AR (0.55) | ALDH1A1MAPTSMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL9655279 | 0.81 | TTR (0.53) | CREBBPALDH1A1MAPTHPGDPRKCI | |
| SCHEMBL9658589 | 0.81 | MAPT (0.42) | CREBBPALDH1A1MAPTHPGDPRKCI | |
| SCHEMBL9657613 | 0.78 | CREBBP (0.41) | CREBBPALDH1A1MAPTPRKCISMN1; SMN2 | |
| SCHEMBL9658224 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDSMN1; SMN2TSHR | |
| SCHEMBL9658204 | 0.77 | CREBBP (0.46) | CREBBPALDH1A1MAPTPRKCIMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |