SCHEMBL9655529

SCHEMBL9655529

C=CCCC/C=C/CC=C(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
USP2 O75604 1/20 0.34
CYP3A4 P08684 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TRPV1 Q8NER1 1/20 0.32
ALOX15 P16050 1/20 0.32
CNR1 P21554 1/20 0.32
F7 P08709 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP19A1 P11511 1/20 0.31
F3 P13726 1/20 0.31
RXRA P19793 1/20 0.31
PTGS1 P23219 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655533 1.00 TSHR (0.37) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL9229665 0.84 SQLE (0.40) TSHRALDH1A1MAPTCYP3A4ALOX15
SCHEMBL6201373 0.80 TSHR (0.39) TSHRALDH1A1LMNAMAPTALOX15
SCHEMBL43730 0.79
SCHEMBL7278067 0.77 PPARG (0.44) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL9408476 0.77 TSHR (0.48) TSHRALDH1A1LMNAMAPTUSP2
SCHEMBL19876340 0.77 ALDH1A1 (0.35) TSHRALDH1A1LMNAMAPTCYP3A4
SCHEMBL19876339 0.77 ALDH1A1 (0.35) TSHRALDH1A1LMNAMAPTCYP3A4
SCHEMBL3720954 0.77 TSHR (0.46) TSHRALDH1A1LMNAMAPTCYP3A4
SCHEMBL5140414 0.77 TSHR (0.44) TSHRALDH1A1MAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4522735-A Polyphosphoramidite oligomers and stabilizer compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-06-11 US claimed
US-5096949-A Heat and oxidation resistance, photostability; polyolefins; uv rad THE B. F. GOODRICH COMPANY (US) 1992-03-17 US disclosed
US-4920228-A N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith THE B. F. GOODRICH COMPANY (US) 1990-04-24 US disclosed
US-4780495-A HEAT, OXIDATION, AND LIGHT STABILIZERS THE B. F. GOODRICH COMPANY (US) 1988-10-25 US disclosed
EP-0141419-B1 3,5-DIALKYL-4-HYDROXYPHENYL-SUBSTITUTED DERIVATIVES The B.F. GOODRICH Company (US) 1988-03-09 EP disclosed
EP-0106169-B1 SUBSTITUTED 2-(2,6-DI-T-BUTYL-4-ALKYLPHENOXY) 4H-1,3,2-BENZODIOXAPHOSPHORINS AND COMPOSITIONS THEREOF The B.F. GOODRICH Company (US) 1988-01-07 EP disclosed
EP-0128368-B1 2,4,6-TRIS(SUBSTITUTED PHENOXY)-1,3,5,2,4,6-TRIOXATRIPHOSPHORINANES The B.F. GOODRICH Company (US) 1987-08-12 EP disclosed
US-4584146-A Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites THE B. F. GOODRICH COMPANY (US) 1986-04-22 US disclosed
US-4529533-A Substituted 2-(2,6-di-t-butly-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-07-16 US disclosed
US-4522735-A Polyphosphoramidite oligomers and stabilizer compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-06-11 US disclosed
EP-0110293-A2 Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof The B.F. GOODRICH Company (US) 1984-06-13 EP disclosed
EP-0106169-A1 Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof The B.F. GOODRICH Company (US) 1984-04-25 EP disclosed
US-4444929-A Unsymmetrical phosphite-phenolic isocyanurate stabilizer combinations THE B. F. GOODRICH COMPANY (US) 1984-04-24 US disclosed
EP-0104643-A2 5-Membered cyclic phosphonates and compositions thereof The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4439564-A 5-Membered cyclic phosphonates and compositions thereof THE B. F. GOODRICH CO. (US) 1984-03-27 US disclosed
US-4415686-A Sterically hindered phenyl bis(naphthyl)phosphites and compositions thereof THE B. F. GOODRICH COMPANY (US) 1983-11-15 US disclosed
US-4066619-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1978-01-03 US disclosed
US-4055540-A STABILIZERS FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-10-25 US disclosed
US-4048140-A 2-HYDROXY-DIPHENYL SULFOXIDE THE B. F. GOODRICH COMPANY (US) 1977-09-13 US disclosed
US-4032505-A FROM BENZENESULFINYL CHLORIDE AND RESORCINOL, PHOTOSTABILIZER FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1977-06-28 US disclosed