SCHEMBL9655604

SCHEMBL9655604

CC(C)=C1CC(=O)N(c2cc(OC(F)F)c(Cl)cc2F)C1=O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPOX P50336 10/20 0.41
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655971 0.92 GAA (0.38) PPOXALDH1A1LMNAHTTGAA
SCHEMBL9654777 0.91 PPOX (0.50) PPOXHTTGAA
SCHEMBL9653011 0.87 PPOX (0.54) PPOXALDH1A1LMNAHTTGAA
SCHEMBL9652912 0.87 PPOX (0.46) PPOXGAAPKM
SCHEMBL9655287 0.86 PPOX (0.47) PPOXGAAPKM
SCHEMBL9654775 0.86 PPOX (0.41) PPOXALDH1A1LMNAHTTGAA
SCHEMBL9652965 0.86 PPOX (0.41) PPOXALDH1A1LMNAHTT
SCHEMBL9655624 0.85 PPOX (0.51) PPOXALDH1A1LMNAHTTGAA
SCHEMBL9652920 0.84 PPOX (0.53) PPOX
SCHEMBL9652576 0.84 PPOX (0.43) PPOXGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed