Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KLK3 | P07288 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Benzoate SCHEMBL10525448 | 0.88 | KMT2A (0.82) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL312910 | 0.88 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL13469247 | 0.85 | TDP1 (0.71) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL318600 | 0.85 | TDP1 (0.71) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL15012759 | 0.85 | TDP1 (0.71) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL9656735 | 0.85 | HTT (0.63) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL31455827 | 0.85 | RAB9A (0.61) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL23736438 | 0.85 | KMT2A (0.76) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL20893057 | 0.84 | TDP1 (0.65) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL16758178 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268343-B1 | ENZYMATIC PROCESS FOR 3-SUBSTITUTED CEPHALOSPORINS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1992-05-27 | — | — | EP | disclosed |
| EP-0268343-A2 | Enzymatic process for 3-substituted cephalosporins | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-05-25 | — | — | EP | disclosed |
| EP-0260778-A1 | Enzymatic process for B-Lactams | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-03-23 | — | — | EP | disclosed |