Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 5/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657153 | 0.89 | MEP1B (0.50) | FOLH1MEP1BANPEPENPEPFNTA | |
| SCHEMBL9654344 | 0.89 | MEP1B (0.50) | FOLH1MEP1BANPEPENPEPFNTA | |
| SCHEMBL10698881 | 0.81 | FOLH1 (0.57) | FOLH1MEP1BANPEPENPEPFNTA | |
| SCHEMBL15387514 | 0.77 | MME (0.55) | MME | |
| SCHEMBL9633609 | 0.77 | MME (0.55) | MME | |
| SCHEMBL15387515 | 0.77 | MME (0.55) | MME | |
| SCHEMBL9655967 | 0.76 | ANPEP (0.43) | FOLH1MEP1BANPEPENPEPMRGPRX4 | |
| SCHEMBL9655961 | 0.76 | ANPEP (0.47) | FOLH1ANPEPENPEPMRGPRX4FNTA | |
| SCHEMBL16115820 | 0.75 | POLB (0.54) | RAB9ASMN1; SMN2 | |
| SCHEMBL10700246 | 0.74 | FOLH1 (0.43) | FOLH1MEP1BANPEPENPEPFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268343-B1 | ENZYMATIC PROCESS FOR 3-SUBSTITUTED CEPHALOSPORINS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1992-05-27 | — | — | EP | disclosed |
| EP-0268343-A2 | Enzymatic process for 3-substituted cephalosporins | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-05-25 | — | — | EP | disclosed |