Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655956 | 1.00 | MAPT (0.63) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL10335322 | 0.86 | MAPT (0.63) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL31005089 | 0.83 | MAPT (0.78) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL10511247 | 0.81 | RAB9A (0.74) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL31549843 | 0.79 | KDM4E (0.56) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL16035626 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL14907039 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL16035627 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL19472642 | 0.77 | MEN1 (1.00) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL17689262 | 0.77 | MAPT (0.65) | MAPTMEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299974-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0299974-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006127-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |