Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655972 | 0.90 | AGTR1 (0.46) | — | |
| SCHEMBL9317987 | 0.90 | PPARG (0.34) | PPARG | |
| SCHEMBL9653422 | 0.88 | — | — | |
| SCHEMBL9318393 | 0.88 | PPARG (0.46) | PPARG | |
| SCHEMBL9318246 | 0.84 | AGTR1 (0.48) | — | |
| SCHEMBL9318652 | 0.81 | — | — | |
| SCHEMBL9318049 | 0.80 | AGTR1 (0.49) | PPARG | |
| SCHEMBL9317983 | 0.80 | — | — | |
| SCHEMBL9318731 | 0.79 | — | — | |
| SCHEMBL9318390 | 0.78 | AGTR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514197-A1 | Anti-hypertensive benzofuran derivatives substituted by N-imidazolyl-methyl groups which are condensed with optionally nitrogen containing, six-membered rings | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |