Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656146 | 1.00 | KMO (0.35) | KMOGRIK1GRIK2CYP3A4TSHR | |
| SCHEMBL9329084 | 0.87 | GAA (0.35) | CYP3A4TSHRMAPTALDH1A1GAA | |
| SCHEMBL9763394 | 0.77 | AKR1C3 (0.42) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL9330262 | 0.77 | GAA (0.39) | CYP3A4TSHRMAPTALDH1A1GAA | |
| SCHEMBL9655352 | 0.77 | GAA (0.39) | CYP3A4TSHRMAPTALDH1A1GAA | |
| SCHEMBL9656936 | 0.75 | GRIK1 (0.47) | KMOGRIK1GRIK2CYP3A4TSHR | |
| SCHEMBL9656928 | 0.75 | GRIK1 (0.47) | KMOGRIK1GRIK2CYP3A4TSHR | |
| SCHEMBL7727179 | 0.72 | CYP3A4 (0.41) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL7727183 | 0.72 | CYP3A4 (0.41) | CYP3A4TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL9305897 | 0.71 | GAA (0.41) | CYP3A4TSHRMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123955-A | Herbicides, chloro and tetrahydrophthalimido-substituted phenyl | PLATH PETER (DE) | 1992-06-23 | — | — | US | disclosed |
| US-4933001-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |