Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654708 | 0.98 | LMNA (0.44) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL29700497 | 0.98 | LMNA (0.44) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL29700322 | 0.94 | KCNH2 (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL9654902 | 0.94 | KCNH2 (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL9629330 | 0.89 | MEN1 (0.49) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL9628492 | 0.89 | MEN1 (0.49) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL9657777 | 0.89 | LMNA (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL4129980 | 0.88 | MEN1 (0.48) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL9629502 | 0.86 | MEN1 (0.46) | MEN1KMT2ALMNANR1I2CHRM2 | |
| SCHEMBL9627600 | 0.86 | MEN1 (0.46) | MEN1KMT2ALMNANR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |