Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGL | P35573 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | LCT | P09848 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656346 | 1.00 | AGL (0.44) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL3426929 | 0.88 | SPHK2 (0.35) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL3430988 | 0.88 | SPHK2 (0.35) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL7617507 | 0.88 | SPHK2 (0.35) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL16508748 | 0.83 | AGL (0.37) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL3430986 | 0.80 | PNP (0.34) | AGLGAAMGAMGBA1SI | |
| SCHEMBL3426927 | 0.80 | PNP (0.34) | AGLGAAMGAMGBA1SI | |
| SCHEMBL23913040 | 0.79 | SPHK1 (0.39) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL20862256 | 0.79 | SPHK1 (0.39) | AGLGAAMGAMTDP1GBA1 | |
| SCHEMBL3442530 | 0.79 | PNP (0.34) | PNPSPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089491-A | Active against both gram-negative and gram-positive bacteria | EISAI CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0264091-B1 | 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-5066812-A | Chemical intermediates for bactericides | EISAI CO., LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| US-5006649-A | Bactericides | EISAI, CO. (JP) | 1991-04-09 | — | — | US | disclosed |
| US-4921850-A | GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE | EISAI CO., LTD. (JP) | 1990-05-01 | — | — | US | disclosed |