Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 17/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 15/20 | 0.38 |
| ▸ | AGL | P35573 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LCT | P09848 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913040 | 1.00 | SPHK1 (0.39) | SPHK1SPHK2AGLGAATDP1 | |
| SCHEMBL23912945 | 0.85 | GBA1 (0.50) | SPHK1SPHK2GAAGBA1 | |
| SCHEMBL20726262 | 0.85 | GBA1 (0.50) | SPHK1SPHK2GAAGBA1 | |
| SCHEMBL19512642 | 0.82 | GBA2 (0.53) | SPHK1SPHK2AGLGAAMGAM | |
| SCHEMBL23517199 | 0.82 | GBA2 (0.53) | SPHK1SPHK2AGLGAAMGAM | |
| SCHEMBL20726313 | 0.80 | SPHK1 (0.37) | SPHK1SPHK2GAAGBA1 | |
| SCHEMBL20726306 | 0.80 | SPHK1 (0.37) | SPHK1SPHK2GAAGBA1 | |
| SCHEMBL9656350 | 0.79 | AGL (0.44) | SPHK1SPHK2AGLGAATDP1 | |
| SCHEMBL9656346 | 0.79 | AGL (0.44) | SPHK1SPHK2AGLGAATDP1 | |
| SCHEMBL23996474 | 0.79 | SPHK1 (0.43) | SPHK1SPHK2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138099-A1 | PREPARATION METHOD FOR MIGLITTOL | 浙江奥翔药业股份有限公司 | 2023-07-27 | — | — | WO | disclosed |
| EP-3461812-A1 | N-(5-(BIPHEN-4-YLMETHYLOXY)PENTYL)-SUBSTITUTED IMINOSUGARS AS INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | Academisch Medisch Centrum (NL) | 2019-04-03 | — | — | EP | disclosed |