SCHEMBL9656380

SCHEMBL9656380

CCCCCCNC(=O)Oc1cc(OCCCCCC)c(OC(=O)NCCCCCC)c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.49
MGLL Q99685 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9657132 0.97 NCEH1 (0.48) NCEH1MGLL
SCHEMBL9654590 0.93 NCEH1 (0.49) NCEH1MGLL
SCHEMBL9656968 0.92 NCEH1 (0.53) NCEH1
SCHEMBL9657983 0.89 SLC2A1 (0.50) NCEH1MGLL
SCHEMBL9656335 0.89 MGLL (0.58) NCEH1MGLL
SCHEMBL9659318 0.88 SLC2A1 (0.53) NCEH1MGLL
SCHEMBL9660542 0.88 NCEH1 (0.51) NCEH1
SCHEMBL9658031 0.88 NCEH1 (0.54) NCEH1
SCHEMBL9659110 0.87 NCEH1 (0.53) NCEH1
SCHEMBL9656336 0.87 NCEH1 (0.44) NCEH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed