Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657911 | 0.96 | KMT2A (0.43) | KMT2ACNR1CNR2HTTPDE10A | |
| SCHEMBL9659104 | 0.95 | KMT2A (0.42) | KMT2ACNR1CNR2HTTPDE10A | |
| SCHEMBL9656999 | 0.90 | TSHR (0.41) | KMT2AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL9657067 | 0.87 | CNR1 (0.43) | CNR1CNR2HTTPKMALDH1A1 | |
| SCHEMBL9660468 | 0.85 | TSHR (0.42) | KMT2AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL9660550 | 0.84 | SLC2A1 (0.44) | KMT2AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL9656721 | 0.84 | KMT2A (0.44) | KMT2ACNR1CNR2HTTPDE10A | |
| SCHEMBL9656624 | 0.84 | ELANE (0.46) | KMT2ACNR1CNR2HTTALDH1A1 | |
| SCHEMBL9659324 | 0.83 | CNR1 (0.44) | KMT2ACNR1CNR2HTTPKM | |
| SCHEMBL9659432 | 0.83 | CNR1 (0.44) | KMT2ACNR1CNR2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |