Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656999 | 0.96 | TSHR (0.41) | TSHRPOLBCASP6L3MBTL1GLA | |
| SCHEMBL9660550 | 0.90 | SLC2A1 (0.44) | TSHRPOLBCASP6L3MBTL1GLA | |
| SCHEMBL9657911 | 0.89 | KMT2A (0.43) | POLBCASP6ALDH1A1KMT2AMAPT | |
| SCHEMBL9660597 | 0.86 | CASP3 (0.44) | TSHRL3MBTL1GLASLC2A1CASP3 | |
| SCHEMBL9659440 | 0.86 | SLC2A1 (0.46) | TSHRL3MBTL1GLASLC2A1KMT2A | |
| SCHEMBL9656386 | 0.85 | KMT2A (0.42) | POLBCASP6ALDH1A1KMT2AMAPT | |
| SCHEMBL9656404 | 0.84 | PTGER4 (0.42) | TSHRPOLBCASP6L3MBTL1GLA | |
| SCHEMBL9658081 | 0.83 | KDM4E (0.46) | POLBL3MBTL1CASP3CASP7CASP9 | |
| SCHEMBL9628409 | 0.82 | HTT (0.56) | TSHRL3MBTL1GLASLC2A1CASP3 | |
| SCHEMBL9659086 | 0.82 | SLC2A1 (0.41) | TSHRL3MBTL1GLASLC2A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |