Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654675 | 0.86 | TDP1 (0.39) | HTTTDP1TSHRCYP3A4KDM4E | |
| SCHEMBL9657924 | 0.85 | HTT (0.42) | GLAHTTTSHRKDM4EKMT2A | |
| SCHEMBL23271841 | 0.84 | HTT (0.41) | L3MBTL1GLAHTTSLC2A1TDP1 | |
| SCHEMBL30003359 | 0.84 | HTT (0.41) | L3MBTL1GLAHTTSLC2A1TDP1 | |
| SCHEMBL9659440 | 0.83 | SLC2A1 (0.46) | L3MBTL1GLAHTTSLC2A1TSHR | |
| SCHEMBL9656659 | 0.83 | TDP1 (0.40) | L3MBTL1GLASLC2A1TDP1TSHR | |
| SCHEMBL9656999 | 0.83 | TSHR (0.41) | L3MBTL1GLAHTTSLC2A1TSHR | |
| SCHEMBL9660454 | 0.82 | SLC2A1 (0.49) | L3MBTL1GLAHTTSLC2A1TSHR | |
| SCHEMBL9657686 | 0.82 | HTT (0.40) | L3MBTL1GLAHTTSLC2A1TSHR | |
| SCHEMBL9658296 | 0.82 | HTT (0.40) | L3MBTL1HTTTSHRKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |