Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657924 | 0.85 | HTT (0.42) | HTTPOLBLMNACYP1A2CYP2C9 | |
| SCHEMBL9657784 | 0.85 | KMT2A (0.42) | HTTTTRPOLBLMNAL3MBTL1 | |
| SCHEMBL9656577 | 0.83 | TSHR (0.39) | PTGS1LMNACYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL9656391 | 0.82 | L3MBTL1 (0.40) | HTTLMNAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9659409 | 0.81 | KDM4E (0.44) | HTTTTRPOLBLMNAL3MBTL1 | |
| SCHEMBL9658026 | 0.81 | TTR (0.47) | TTRPOLBLMNACYP1A2CYP2C9 | |
| SCHEMBL10707130 | 0.81 | ELANE (0.42) | HTTPTGS1TTRPOLBLMNA | |
| SCHEMBL23271694 | 0.81 | HTT (0.61) | HTTPOLBLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL30004224 | 0.81 | HTT (0.61) | HTTPOLBLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9656394 | 0.80 | LMNA (0.40) | HTTPOLBLMNAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |