Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656438 | 1.00 | LMNA (0.46) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL10996466 | 0.88 | LMNA (0.45) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL10996469 | 0.88 | LMNA (0.45) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL902763 | 0.87 | LMNA (0.41) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL95469 | 0.85 | MEN1 (0.60) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL22616865 | 0.85 | MEN1 (0.60) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL560387 | 0.85 | MEN1 (0.60) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL477467 | 0.83 | CYP1A2 (0.57) | LMNACYP2D6 | |
| SCHEMBL10411854 | 0.83 | CYP1A2 (0.52) | LMNAMAPK1TSHR | |
| SCHEMBL477645 | 0.83 | CYP1A2 (0.57) | LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151333-A | Containing imine derivative | NIPPON ZEON CO., LTD (JP) | 1992-09-29 | — | — | US | disclosed |
| US-3975381-A | Process for preparing γ-lactone derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JA) | 1976-08-17 | — | — | US | disclosed |