Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660646 | 0.96 | SLC2A1 (0.45) | NCEH1SLC2A1EPHX1HCRTR1ALDH1A1 | |
| SCHEMBL9658010 | 0.95 | SLC2A1 (0.48) | NCEH1SLC2A1EPHX1HCRTR1CES2 | |
| SCHEMBL9658031 | 0.93 | NCEH1 (0.54) | NCEH1SLC2A1HCRTR1 | |
| SCHEMBL9656336 | 0.91 | NCEH1 (0.44) | NCEH1SLC2A1EPHX1ALDH1A1MAPT | |
| SCHEMBL9654590 | 0.90 | NCEH1 (0.49) | NCEH1SLC2A1 | |
| SCHEMBL9659092 | 0.89 | NCEH1 (0.52) | NCEH1SLC2A1HCRTR1 | |
| SCHEMBL9654921 | 0.88 | NCEH1 (0.45) | NCEH1EPHX1ALDH1A1POLB | |
| SCHEMBL9660540 | 0.88 | NCEH1 (0.54) | NCEH1SLC2A1HCRTR1 | |
| SCHEMBL9658056 | 0.87 | NCEH1 (0.42) | NCEH1SLC2A1EPHX1ALDH1A1MAPT | |
| SCHEMBL9657983 | 0.86 | SLC2A1 (0.50) | NCEH1SLC2A1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |