Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656605 | 0.95 | NCEH1 (0.44) | SLC2A1NCEH1HCRTR1CES2EPHX1 | |
| SCHEMBL9660540 | 0.93 | NCEH1 (0.54) | SLC2A1NCEH1HCRTR1TSHR | |
| SCHEMBL9660646 | 0.91 | SLC2A1 (0.45) | SLC2A1NCEH1HCRTR1MEN1KMT2A | |
| SCHEMBL9659318 | 0.90 | SLC2A1 (0.53) | SLC2A1NCEH1 | |
| SCHEMBL9659424 | 0.90 | SLC2A1 (0.47) | SLC2A1HCRTR1MEN1KMT2ATSHR | |
| SCHEMBL9658031 | 0.88 | NCEH1 (0.54) | SLC2A1NCEH1HCRTR1TSHR | |
| SCHEMBL9659401 | 0.86 | POLB (0.50) | SLC2A1NCEH1 | |
| SCHEMBL9656336 | 0.86 | NCEH1 (0.44) | SLC2A1NCEH1MEN1KMT2AEPHX1 | |
| SCHEMBL9654590 | 0.85 | NCEH1 (0.49) | SLC2A1NCEH1 | |
| SCHEMBL9658058 | 0.85 | ALDH1A1 (0.49) | SLC2A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |