SCHEMBL9656642

SCHEMBL9656642

Cc1cccc(C(c2ccccc2)(c2ccccc2)c2cccc(C3=CC=CC3)c2C2=CC=CC2)c1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KCNH2 Q12809 1/20 0.32
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585039 0.91
SCHEMBL9654655 0.90 KIF11 (0.30) KIF11
SCHEMBL7590328 0.78 RGS12 (0.39)
SCHEMBL9657074 0.78 KIF11 (0.35) KIF11
SCHEMBL9282367 0.76
SCHEMBL9657120 0.76 PLK1 (0.37) KCNH2
SCHEMBL10452701 0.75 KIF11 (0.31) KIF11
SCHEMBL9283591 0.75
SCHEMBL3267584 0.74
SCHEMBL7584864 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0339986-B1 NOVEL CATALYST FOR HYDROGENATION OF POLYMER AND PROCESS FOR HYDROGENATING POLYMER WITH THE CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-02 EP claimed