SCHEMBL965708

SCHEMBL965708

COCCOCCn1cc(C)s/c1=N\C(=O)C12CC3CC(CC1C3)C2

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 11/20 0.36
CNR1 P21554 4/20 0.36
XDH P47989 1/20 0.33
EPHX2 P34913 2/20 0.33
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL965710 1.00 CNR2 (0.36) CNR2CNR1XDHEPHX2HSD11B1
SCHEMBL5047207 0.92 CNR2 (0.43) CNR2CNR1EPHX2
SCHEMBL5047213 0.92 CNR2 (0.43) CNR2CNR1EPHX2
SCHEMBL961974 0.85 CNR2 (0.36) CNR2CNR1HSD11B1
SCHEMBL961976 0.85 CNR2 (0.36) CNR2CNR1HSD11B1
SCHEMBL961525 0.83 CNR2 (0.45) CNR2CNR1
SCHEMBL961527 0.83 CNR2 (0.45) CNR2CNR1
SCHEMBL965811 0.83 CNR2 (0.46) CNR2CNR1HSD11B1
SCHEMBL964164 0.83 CNR2 (0.46) CNR2CNR1HSD11B1
SCHEMBL1614272 0.83 HSD11B1 (0.36) CNR2CNR1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024349-B1 COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF ABBVIE INC (US) 2017-08-02 EP disclosed
US-20150231141-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF ABBVIE INC (US) 2015-08-20 US disclosed
US-9006275-B2 Compounds as cannabinoid receptor ligands and uses thereof ABBVIE INC. (US) 2015-04-14 US disclosed
US-20110086855-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF ABBOTT LABORATORIES (US) 2011-04-14 US disclosed
US-7875639-B2 Compounds as cannabinoid receptor ligands and uses thereof ABBOTT LABORATORIES (US) 2011-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150231141-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF CNR1, CNR2, OPRL1 CNR2 2/4885CNR1 1/4885XDH 2967/4885
US-20110086855-A1 NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF CNR1, CNR2, OPRL1 CNR2 2/4885CNR1 1/4885XDH 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.