Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658390 | 0.89 | GABRA1 (0.48) | GABRA1GABRB2TRPA1TAAR1AOC3 | |
| SCHEMBL19478609 | 0.88 | GABRA1 (0.52) | GABRA1GABRB2TRPA1TAAR1AOC3 | |
| SCHEMBL1952363 | 0.84 | SLC6A2 (0.47) | TRPA1TAAR1AOC3ESR1ESR2 | |
| SCHEMBL25215353 | 0.84 | SLC6A2 (0.47) | TRPA1TAAR1AOC3ESR1ESR2 | |
| SCHEMBL1952420 | 0.82 | POLB (0.43) | GABRA1GABRB2TRPA1TAAR1AOC3 | |
| SCHEMBL23231061 | 0.79 | — | — | |
| SCHEMBL6547026 | 0.78 | SLC6A2 (0.49) | TRPA1TAAR1AOC3RIPK1MAOA | |
| SCHEMBL6547230 | 0.78 | SLC6A2 (0.49) | TRPA1TAAR1AOC3RIPK1MAOA | |
| SCHEMBL30394315 | 0.78 | ESR1 (0.64) | GABRA1GABRB2TRPA1TAAR1ESR1 | |
| SCHEMBL2472270 | 0.78 | ESR1 (0.64) | GABRA1GABRB2TRPA1TAAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096949-A | Heat and oxidation resistance, photostability; polyolefins; uv rad | THE B. F. GOODRICH COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4920228-A | N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith | THE B. F. GOODRICH COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| US-4780495-A | HEAT, OXIDATION, AND LIGHT STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1988-10-25 | — | — | US | disclosed |