Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 8/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.43 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541 | 0.96 | — | — | |
| SCHEMBL4773512 | 0.96 | CCR5 (0.67) | CCR5CHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL1338772 | 0.96 | — | — | |
| SCHEMBL1338774 | 0.96 | — | — | |
| SCHEMBL1162548 | 0.96 | — | — | |
| SCHEMBL12526375 | 0.96 | — | — | |
| SCHEMBL260464 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL1613839 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL1613841 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL22288667 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495826-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991004973-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-04-18 | — | — | WO | disclosed |