Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 5/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422124 | 0.86 | PNP (0.38) | LMNAKDM4EGMNNMAPTBLM | |
| SCHEMBL8509316 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL15263324 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL2636631 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL1994115 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL9393256 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL5182595 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL4436402 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A | |
| SCHEMBL11442291 | 0.85 | PYGL (0.39) | LMNAKDM4EGMNNMAPTBLM | |
| SCHEMBL240028 | 0.85 | HIF1A (0.43) | LMNABLMCYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245913-B1 | Process for preparing 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid | RIKER LABORATORIES, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0245913-A1 | Process for preparing 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid | RIKER LABORATORIES, INC. (US) | 1987-11-19 | — | — | EP | disclosed |