Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259551 | 0.84 | CYP1A2 (1.00) | CYP1A2ALDH1A1MAPTCASP6RAB9A | |
| SCHEMBL14322059 | 0.82 | CYP1A2 (0.74) | CYP1A2ALDH1A1MAPTCASP6NPSR1 | |
| Hydrochloric Acid SCHEMBL5138493 | 0.82 | CYP1A2 (0.96) | CYP1A2ALDH1A1MAPTCASP6RAB9A | |
| SCHEMBL133402 | 0.81 | CYP1A2 (0.71) | CYP1A2RPS6KA2ALDH1A1MAPTPOLB | |
| SCHEMBL20945035 | 0.80 | CYP1A2 (0.70) | CYP1A2ALDH1A1MAPTPOLBCASP6 | |
| SCHEMBL7485009 | 0.77 | CYP1A2 (0.71) | CYP1A2ALDH1A1MAPTCASP6RAB9A | |
| SCHEMBL21026687 | 0.77 | CYP1A2 (0.70) | CYP1A2RPS6KA2ALDH1A1MAPTCASP6 | |
| SCHEMBL5821136 | 0.77 | CYP1A2 (0.65) | CYP1A2RPS6KA2ALDH1A1MAPTPOLB | |
| SCHEMBL14321431 | 0.77 | CYP1A2 (0.65) | CYP1A2RPS6KA2ALDH1A1MAPTCASP6 | |
| SCHEMBL20945151 | 0.76 | MAPK1 (0.59) | CYP1A2ALDH1A1MAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516588-A1 | Substituted diaminophtalimides and analogues | CIBA-GEIGY AG (CH) | 1992-12-02 | — | — | EP | disclosed |