Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.33 |
| ▸ | ALDH1B1 | P30837 | 3/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419311 | 0.73 | — | — | |
| SCHEMBL9430870 | 0.71 | ALDH2 (0.36) | ALDH1A1MAPK1KDM4EKMT2AALDH2 | |
| SCHEMBL8507929 | 0.70 | NQO1 (0.48) | ALDH1A1MAPK1KDM4EKMT2AALDH2 | |
| SCHEMBL11851936 | 0.70 | TYMP (0.46) | ALDH1A1KDM4ERAB9AKMT2ATYMP | |
| SCHEMBL16670954 | 0.69 | PON1 (0.31) | PON1MAPK1KDM4ERAB9AKMT2A | |
| SCHEMBL1143449 | 0.68 | APEX1 (0.54) | PON1ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL6573655 | 0.67 | NQO1 (0.38) | SMN1; SMN2NQO1 | |
| SCHEMBL1932837 | 0.64 | ALDH1A1 (0.39) | ALDH1A1MAPK1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11859358 | 0.64 | ALDH1A1 (0.40) | ALDH1A1MAPK1KDM4EALDH2ALDH1A2 | |
| SCHEMBL20414040 | 0.64 | ALDH1A1 (0.33) | PON1ALDH1A1MAPK1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241918-B1 | 1-HYDROXY-2-PYRIDINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM, AS WELL AS INTERMEDIATES FORMED BY THE PREPARATION OF 1-HYDROXY-2-PYRIDINONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4797409-A | FUNGICIDES, YEAST INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0241918-A2 | 1-Hydroxy-2-pyridinones, process for their preparation and medicines containing them, as well as intermediates formed by the preparation of 1-hydroxy-2-pyridinones | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-21 | — | — | EP | disclosed |