Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700338 | 1.00 | HTT (0.52) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL9629408 | 0.82 | EP300 (0.51) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL9629346 | 0.81 | EP300 (0.42) | LMNAEP300KDM4EMAPTMEN1 | |
| SCHEMBL9054405 | 0.80 | EP300 (0.67) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL29700325 | 0.80 | EP300 (0.67) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL9658037 | 0.79 | LMNA (0.46) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL9628372 | 0.77 | MAPT (0.61) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL9628422 | 0.76 | HTT (0.53) | HTTLMNAKDM4EMAPTMCL1 | |
| SCHEMBL29700360 | 0.76 | LMNA (0.50) | HTTLMNAEP300KDM4EMAPT | |
| SCHEMBL28745754 | 0.76 | EP300 (0.51) | HTTLMNAEP300KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114534787-A | Isopentenol gas-phase dehydrogenation catalyst and method | 万华化学集团股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |