Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658593 | 1.00 | MTNR1A (0.33) | MTNR1AMTNR1BCRBNMEN1FAAH | |
| SCHEMBL19449784 | 0.81 | MTNR1A (0.35) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL7190312 | 0.76 | — | — | |
| SCHEMBL11107958 | 0.76 | — | — | |
| SCHEMBL11092667 | 0.76 | MTNR1A (0.33) | MTNR1AMTNR1BTAS2R38 | |
| SCHEMBL11095942 | 0.76 | MTNR1A (0.33) | MTNR1AMTNR1BTAS2R38 | |
| SCHEMBL11092663 | 0.76 | MTNR1A (0.33) | MTNR1AMTNR1BTAS2R38 | |
| SCHEMBL17742738 | 0.75 | — | — | |
| SCHEMBL13019263 | 0.74 | PAOX (0.41) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL7191918 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315716-B1 | METHOD OF MAKING A DIASTEREOMERIC MIXTURE CONTAINING TWO DIASTEREOMERIC N-ACYL-AMINO ACID ESTERS | THE STANDARD OIL COMPANY (US) | 1992-09-02 | — | — | EP | disclosed |
| EP-0315716-A1 | Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters | THE STANDARD OIL COMPANY (US) | 1989-05-17 | — | — | EP | disclosed |
| US-4721803-A | Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters | THE STANDARD OIL COMPANY (US) | 1988-01-26 | — | — | US | disclosed |