SCHEMBL9658657

SCHEMBL9658657

CCCCCc1cccc(-c2cccc(CCCCC)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.59
LIPG Q9Y5X9 3/20 0.59
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PPARG P37231 2/20 0.49
PPARA Q07869 2/20 0.49
CYP3A4 P08684 1/20 0.47
PTGS2 P35354 1/20 0.47
HSD11B1 P28845 1/20 0.46
KCNH2 Q12809 1/20 0.46
GPR84 Q9NQS5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28079356 0.98 LPL (0.61) LPLLIPGTDP1L3MBTL1PPARG
SCHEMBL6059834 0.94 LPL (0.54) LPLLIPGPPARGPPARAHSD11B1
SCHEMBL199210 0.93 LPL (0.52) LPLLIPGTDP1L3MBTL1PPARG
SCHEMBL27694667 0.92 LPL (0.56) LPLLIPGPPARGPPARAHSD11B1
SCHEMBL5551488 0.92 LPL (0.53) LPLLIPGPPARGPPARAHSD11B1
SCHEMBL3126881 0.92 LPL (0.56) LPLLIPGPPARGPPARAHSD11B1
SCHEMBL8518305 0.89 LPL (0.66) LPLLIPGTDP1L3MBTL1PPARG
SCHEMBL11515483 0.88 PSMB5 (0.49) LPLLIPGHSD11B1
SCHEMBL30500519 0.88 PSMB5 (0.49) LPLLIPGHSD11B1
SCHEMBL7145878 0.88 LPL (0.49) LPLLIPGTDP1L3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0475926-A2 Oxidation of dialkyl polyaromatics to dicarboxypolyaromatics MONSANTO COMPANY (US) 1992-03-18 EP disclosed