Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590068 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9430294 | 0.80 | AGTR1 (0.42) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL443392 | 0.80 | LTB4R2 (0.55) | LTB4R2AGTR1 | |
| SCHEMBL9592768 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL446384 | 0.80 | LTB4R2 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL446089 | 0.80 | LTB4R2 (0.52) | LTB4R2AGTR1 | |
| SCHEMBL9430054 | 0.79 | AGTR1 (0.41) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL446830 | 0.79 | LTB4R2 (0.53) | LTB4R2LPAR1AGTR1 | |
| SCHEMBL443676 | 0.79 | LTB4R2 (0.42) | LTB4R2LPAR1AGTR1AGTR2 | |
| SCHEMBL443942 | 0.79 | LTB4R2 (0.62) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490820-A2 | Biphenylyl compounds | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | claimed |
| EP-0490820-A2 | Biphenylyl compounds | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | disclosed |