Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658738 | 1.00 | NPC1 (0.36) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9690040 | 0.89 | KMT2A (0.43) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9690044 | 0.89 | KMT2A (0.43) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9660368 | 0.85 | NPC1 (0.37) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9658754 | 0.85 | KDM4E (0.42) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9658750 | 0.85 | KDM4E (0.42) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9660161 | 0.80 | KDM4E (0.36) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL9660165 | 0.80 | KDM4E (0.36) | NPC1KMT2ARAB9AMEN1LMNA | |
| SCHEMBL4635224 | 0.79 | PDE2A (0.47) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL4635226 | 0.79 | PDE2A (0.47) | KMT2AMEN1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |