SCHEMBL9658807

SCHEMBL9658807

CCCCCCCCCCCCCCCCCCN([C]=O)CCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 4/20 0.44
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ADH1C P00326 2/20 0.35
ADH1A P07327 2/20 0.35
ADH4 P08319 2/20 0.35
S1PR2 O95136 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
S1PR5 Q9H228 1/20 0.35
EPHX1 P07099 4/20 0.34
ADH1B P00325 1/20 0.34
ADH7 P40394 1/20 0.34
GGPS1 O95749 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9660664 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL9660183 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL271829 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL9660645 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL22395234 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL9661735 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL9659073 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL9661146 1.00 DNM1 (0.44) DNM1TSHRTHRBCA12CA1
SCHEMBL271368 0.98 DNM1 (0.40) DNM1TSHRTHRBCA12CA1
SCHEMBL5469943 0.95 DNM1 (0.48) DNM1TSHRTHRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0517262-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-09 EP disclosed